On overcoming the “worse than worst” earthquake

Quinidine. Worse than adverse?

Health of elderly male prisoners: worse than the general population, worse than younger prisoners.

BACKGROUND Assessment of the health of men aged 60 and over in English and Welsh prisons. METHODS 203 men were interviewed from 15 prisons, comprising one-fifth of all sentenced men in this age group in England and Wales. Assessment included semi-structured interviews covering chronic and acute health problems, and recording of major illnesses from the medical notes and prison reception healt...

A cure worse than the disease.

The pending challenge to section 5 of the Voting Rights Act insists the statute is no longer necessary. Should the Supreme Court agree, its ruling is likely to reflect the belief that section 5 is not only obsolete but that its requirements do more harm today than the condition it was crafted to address. In this Essay, Professor Ellen D. Katz examines why the Court might liken section 5 to a de...

Overcoming the Worst-Case Curse for Cryptographic Constructions

Modeling efficient algorithms as polynomial size circuits rather than as polynomial time Turing machines has been the rule with few exceptions in cryptographic constructions which provide “secure versions” of general efficient algorithms. A consequence of this modeling is that the resulting “secure version” of an efficient algorithm A incurs the worst-case runtime of A over all inputs of a cert...

Mutant PTEN in Cancer: Worse Than Nothing

Tumor suppressors block the development of cancer and are often lost during tumor development. Papa et al. show that partial loss of normal PTEN tumor suppressor function can be compounded by additional disruption caused by the expression of inactive mutant PTEN protein. This has significant implications for patients with PTEN gene mutations.